I never did them, but I would think the bank ones are more detrimental but harder for someone to have figured out than the Supply Chest. Seriously? Reported on preview and they still release it?
These still made it to live even though they were reported:
One PC could freeze all monsters that had agro on them.
Stacking tomes (going from alpha/beta to live).
Moving outside boundaries in several quests and back in.
Endless Litany runs for chests with tome piece chests.
Entering Reaver after completion with any level character.
Using skills ignoring the timer cooldown.
Casting without timers.
Handwraps of death (and lag).
Bags full of power crystals for Titan.
Instant Maraud the Mines XP.
Shroud items outside of shroud.
Abbot hand-of-God.
Necro Sigil duping.
Renown farming.
Endless Epic chests (not ransacking).
Summoned monsters would freeze bosses.
Not really exploit but they screwed us:
Additional slot for every 1750 character (I had 16 when they announced they would reduce it but not sure how - those fucktards).
Endless Earth elementals (well, as many as you made items to summon). Before the store and hirelings, this was an army to beat the snot out of most dungeons.